John J Lima Selected Research

Lansoprazole (Prevacid)

1/2019	Genotype tailored treatment of mild symptomatic acid reflux in children with uncontrolled asthma (GenARA): Rationale and methods.
7/2015	Reply: worsening asthma control in children taking lansoprazole: possible mechanisms.
6/2015	Lansoprazole Is Associated with Worsening Asthma Control in Children with the CYP2C19 Poor Metabolizer Phenotype.
8/2014	Pharmacogenomic testing: the case for CYP2C19 proton pump inhibitor gene-drug pairs.
9/2013	Association of CYP2C19 polymorphisms and lansoprazole-associated respiratory adverse effects in children.
9/2013	Obesity in children with poorly controlled asthma: Sex differences.
1/2012	Lansoprazole for children with poorly controlled asthma: a randomized controlled trial.

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John J Lima Research Topics

Disease

45	Asthma (Bronchial Asthma) 12/2021 - 09/2002
7	Gastroesophageal Reflux (GERD) 01/2021 - 09/2006
6	Infections 01/2021 - 03/2013
5	Respiratory Tract Infections (Respiratory Tract Infection) 06/2015 - 01/2012
4	Inflammation (Inflammations) 01/2017 - 11/2003
4	Obesity 09/2013 - 06/2007
2	Overweight 01/2019 - 04/2015
2	Chronic Disease (Chronic Diseases) 01/2017 - 05/2015
1	Duodenal Ulcer (Curling's Ulcer) 01/2021
1	Esophagitis 01/2021
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 12/2019
1	Eosinophilic Esophagitis 11/2019
1	Eosinophilia 11/2019
1	Vitamin D Deficiency 01/2017
1	Fever (Fevers) 08/2016
1	Pain (Aches) 08/2016
1	Chronic Obstructive Pulmonary Disease (COPD) 02/2015
1	Respiratory Hypersensitivity 06/2013
1	Airway Obstruction (Choking) 07/2012
1	Cardiovascular Diseases (Cardiovascular Disease) 09/2007
1	Insulin Resistance 06/2007

Drug/Important Bio-Agent (IBA)

9	Proton Pump InhibitorsIBA 01/2021 - 01/2012
9	Bronchodilator Agents (Bronchodilators)IBA 01/2017 - 09/2002
9	LeukotrienesIBA 03/2014 - 10/2003
8	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2021 - 01/2007
8	Cytochrome P-450 CYP2C19IBA 12/2019 - 09/2013
7	Pharmaceutical PreparationsIBA 12/2021 - 04/2007
7	Lansoprazole (Prevacid)FDA LinkGeneric 01/2019 - 01/2012
6	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2017 - 09/2002
5	AcidsIBA 01/2021 - 01/2012
5	montelukast (Singulair)FDA Link 01/2015 - 11/2003
4	GlucocorticoidsIBA 01/2019 - 09/2011
4	Biomarkers (Surrogate Marker)IBA 12/2018 - 03/2013
3	Vitamin D FDA LinkGeneric 10/2018 - 02/2015
3	Leukotriene Antagonists (Leukotriene Receptor Antagonists)IBA 01/2018 - 10/2003
3	Adrenergic Receptors (Adrenergic Receptor)IBA 09/2014 - 04/2006
3	Theophylline (Theon)FDA LinkGeneric 05/2008 - 09/2006
2	Fluticasone (Cutivate)FDA LinkGeneric 12/2021 - 03/2018
2	EnzymesIBA 01/2018 - 10/2003
2	Immunoglobulin E (IgE)IBA 12/2017 - 01/2017
2	hydroxide ionIBA 01/2017 - 01/2017
2	CotinineIBA 01/2017 - 03/2013
2	Albuterol (Salbutamol)FDA LinkGeneric 08/2016 - 05/2008
1	DNA (Deoxyribonucleic Acid)IBA 11/2019
1	Fish OilsIBA 01/2019
1	Carbon MonoxideIBA 12/2018
1	Cholecalciferol (Vitamin D3)FDA Link 10/2018
1	zileuton (Zyflo)FDA Link 01/2018
1	Folic Acid (Vitamin M)FDA LinkGeneric 12/2017
1	AntigensIBA 01/2017
1	Acetaminophen (Paracetamol)FDA LinkGeneric 08/2016
1	Ibuprofen (Motrin)FDA LinkGeneric 08/2016
1	IsoflavonesIBA 05/2015
1	Methacholine Chloride (Methacholine)FDA Link 04/2015
1	3- (2- (4- azidobenzamidino)ethyl)- 5- hydroxyindole (SABA)IBA 09/2014
1	Salmeterol Xinafoate (Serevent)FDA Link 03/2014
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 03/2013
1	Leukotriene E4IBA 03/2013
1	Biological ProductsIBA 03/2013
1	SmokeIBA 03/2013
1	Kv Channel-Interacting Proteins (Calsenilin)IBA 01/2013
1	Complement System Proteins (Complement)IBA 01/2009
1	Corticotropin-Releasing Hormone Receptors (Corticotropin Releasing-Hormone Receptor)IBA 05/2008
1	Corticotropin-Releasing HormoneIBA 05/2008
1	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 09/2007
1	LipidsIBA 09/2007
1	PotassiumIBA 06/2007
1	CatecholaminesIBA 06/2007
1	Glucose (Dextrose)FDA LinkGeneric 06/2007
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 06/2007
1	Insulin (Novolin)FDA Link 06/2007
1	CytokinesIBA 09/2006
1	leukotriene-C4 synthaseIBA 11/2003
1	Leukotriene C4IBA 10/2003
1	SteroidsIBA 09/2002

Therapy/Procedure

16	Therapeutics 12/2021 - 01/2007
2	Airway Management 09/2013 - 12/2011
1	Operative Surgical Procedures 01/2018
1	Nebulizers and Vaporizers (Inhaler) 08/2016
1	Precision Medicine 01/2009
1	Drug Therapy (Chemotherapy) 09/2008